- Bug fix for the approximate Firth test when ultra-rare variants (MAC<50) are being tested:
- Fix to the calculation of the null deviance used in the likelihood ratio test.
- BETA estimates remain unchanged, but p-value will change (SE will also change if using
--firth-se). - This fix also addresses convergence failures with Firth.
- Improvements to address convergence failures & speed-up exact Firth by using warm starts based on null model with just covariates.