github chrchang/plink-ng v2.0.0-a.7.12
Alpha 7.12: --geno-counts at chrX multiallelic variants, multiallelic-variant allele uniqueness check, --keep-cats/--keep-cat-names with no match, other bugfixes

4 hours ago
  • --split-par no longer mislabels the first variant in the next chromosome when all chrX variants are in PAR1.
  • --indep-pairphase no longer makes misaligned memory allocations (which can result in a crash) in non-AVX2 64-bit builds.
  • --adjust[-file] + --pfilter no longer crashes when printing the final log line.
  • --hwe "observation counts vary by more than 10%" warning now works properly.
  • --geno-counts now correctly handles male counts at chrX multiallelic variants.
  • Fixed cubic-solver edge case which occasionally resulted in spurious NaNs or crashes in --r2-phased, --clump (without --clump-unphased), and --ld.
  • Fixed "--missing scols=" and "--sample-counts cols=" command-line parsing/validation bugs.
  • --no-categorical now works as intended on apparently-categorical .psam columns.
  • --keep-cats/--keep-cat-names now remove all samples (resulting in a downstream error) instead of no samples when there are no matching categories.
  • Allele-uniqueness check (invoked by --score, --pgen-diff, --rm-dup, --update-alleles, --read-freq, --alt-allele, --ref-from-fa, and --clump) now works properly on multiallelic variants.
  • --merge-filter-mode now has the documented 'np-union' default, instead of 'nm-first'.

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