For Ensembl VEP 115.0 we have:
- Added Ensembl VEP support for annotating structural variants with allele frequencies from gnomAD and clinical significance (CLINSIG) from ClinVar.
- Added Ensembl VEP and Ensembl Variation API support for the new ClinVar somatic classifications.
- Enabled support for GENCODE promoters, variants falling within them can now be annotated with details of the promoter
- Added a new plugin (on CLI): MechPredict